A renowned scientist in the field of genetics - mainly in organism genetics.
His legacy is as a Drosophila researcher. He launched a Newsletter called the Drosophila Information Service in 1934 with Calvin Bridges. He also pioneered, alongside other scientists, in the initial field of X-ray- and UV- induced mutations. He wrote many publications including research papers. He was the founding editor of Advances in Genetics, the first publication to appraise the results of modern genetics. Among his many achievements, he was appointed to many scientific panels including the committee on the Biological Effects of Atomic Radiation under the National Academy of sciences and served various departments in different capacities.
Demerec was known for his efficiency as he used means and tools that served him best in his research. He is credited for promoting the sprouting field of molecular biology.